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Figure 1 | BMC Genomics

Figure 1

From: Comparative genomic mapping of the bovine Fragile Histidine Triad (FHIT) tumour suppressor gene: characterization of a 2 Mb BAC contig covering the locus, complete annotation of the gene, analysis of cDNA and of physiological expression profiles

Figure 1

VISTA Global Alignments of the human and bovine FHIT loci. VISTA plot showing sequence similarity in pairwise sequence alignments between the human sequence at the FHIT locus [Genbank:NC_000003.1] nt 59500000 to 61500000; the FHIT gene coordinates are nt 59710076 to 61212164] and bovine genomic contigs: 1. [Genbank:NW_978846]; 2. [Genbank:NW_001018446]; 3. [Genbank:NW_984819]; 4. [Genbank:NW_930116_B] (Reverse-complement of the original [Genbank:NW_930116] from nt 84000 to the 3' end); 5. [Genbank:NW_935020]; 6. [Genbank:NW_930116_A] (the initial 84000 nt of the original [Genbank:NW_930116]); 7. [Genbank:NW_977438]; 8. [Genbank:NW_968990]. Peaks are shown relative to their position in the reference human sequence (horizontal axis) and percent identity (50–100%) is shown on the vertical axis. Color code is predominantly pink (non coding sequence) as exons (in blue) are virtually invisible due to their very small size (49 to 317 bp).

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