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Figure 4 | BMC Genomics

Figure 4

From: Causal inference of regulator-target pairs by gene mapping of expression phenotypes

Figure 4

Multiple regulators. A plot of recall ( T P T P + F N ) MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacH8akY=wiFfYdH8Gipec8Eeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=vr0dc8meaabaqaciaacaGaaeqabaqabeGadaaakeaadaqadaqaamaalaaabaGaemivaqLaemiuaafabaGaemivaqLaemiuaaLaey4kaSIaemOrayKaemOta4eaaaGaayjkaiaawMcaaaaa@3615@ precision ( T P T P + F P ) MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacH8akY=wiFfYdH8Gipec8Eeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=vr0dc8meaabaqaciaacaGaaeqabaqabeGadaaakeaadaqadaqaamaalaaabaGaemivaqLaemiuaafabaGaemivaqLaemiuaaLaey4kaSIaemOrayKaemiuaafaaaGaayjkaiaawMcaaaaa@3619@ for varying full model scores. QTG: our model; a positive classification is a regulator whose score exceeds the threshold; Multiple plots for QTG are shown for k = 2 ... 5 as the number of additional regulators in the regulon, i.e. extra noise terms. QTL: the conventional QTL score where a positive is measured as with QTG; QTLI: an easier test using the QTL score where a true positive is called when the true regulator gene is found within the QTL interval.

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