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Table 5 List of biological processes and statistics of the corresponding Alu content in the 5 kbp upstream regions of the associated genes.

From: Alu elements contain many binding sites for transcription factors and may play a role in regulation of developmental processes

Biological process

number of genes

number of Alu

Average number per gene

Ttest p-value

central nervous system development

86

167

1.94

1.73E-06

skeletal development

105

210

2.00

2.13E-07

potassium ion transport

128

270

2.11

9.41E-08

organogenesis

816

1986

2.43

4.63E-25

cell-cell adhesion

114

281

2.46

1.28E-04

neurogenesis

335

835

2.49

2.20E-10

cell-cell signaling

470

1190

2.53

3.18E-13

morphogenesis

1010

2606

2.58

9.42E-24

cell adhesion

471

1288

2.74

2.54E-09

muscle development

150

412

2.74

7.95E-04

sensory perception

234

646

2.76

3.76E-05

ion transport

573

1595

2.78

5.06E-10

inflammatory response

181

507

2.80

5.50E-04

development

1519

4274

2.81

3.92E-21

immune response

635

1853

2.92

4.21E-08

response to external stimulus

910

2727

3.00

7.05E-09

cell communication

2535

7885

3.11

3.66E-14

signal transduction

2017

6538

3.24

2.79E-07

genome

13686

49748

3.63

1

metabolism

5605

21936

3.91

6.85E-08

cell cycle

651

2751

4.23

5.56E-06

biosynthesis

899

3827

4.26

2.92E-08

intracellular transport

406

1840

4.53

3.86E-08

protein localization

418

1981

4.74

7.15E-12

protein biosynthesis

452

2155

4.77

3.24E-13

mrna processing

205

1006

4.91

2.37E-08

rna processing

322

1611

5.00

6.70E-14

rna splicing

173

872

5.04

1.42E-08

rna metabolism

391

1987

5.08

3.66E-18

ribosome biogenesis

43

223

5.19

1.62E-03

translation

138

743

5.39

2.62E-10