Skip to main content

Table 7 BMs with target sites on B1_mM and B1_Mus ('Alu Like' sequence in mouse). The scores of the target sites were above T5 (those for which the corresponding ALU BS had scores greater than T5 are in bold). The IUPAC convention [33] consensus sites are in column 2, and the third column shows the target site with the highest score among all the major consensus sequence (nucleotides that agree with the consensus are denoted with capital letters). The location of the putative target sites is in column 4, given for the subfamily on which the target site of column 3 appears. Column 6 lists the number, n, of B1 subfamilies on which the BS shown in column 3 is located.

From: Alu elements contain many binding sites for transcription factors and may play a role in regulation of developmental processes

BM name

Consensus

Binding site

location

p-val

n

V$ATF6.01

SNGCCACNNNNNN

CCaCCACGCCCGG

B1_Mm (-3:-15)

2.8E-02

1

V$ZBRK1_01

SGGGSMRCAGNYMTTTKTKKSC

GGtGGCGCAcGCCTTTaaTcCC

B1_Mm (11:32)

2.9E-02

2

V$BRN3.02

NNYYWKTAATYWNWY

CGCCTTTAATCcCAg

B1_Mm (20:34)

3.9E-02

2

V$GKLF_02

NTYAMAGGRN

ATTAAAGGcG

B1_Mm (-20:-29)

1.1E-02

2

V$CRX.01

NNNGATTARNNT

TGGGATTAAAGg

B1_Mm (-22:-33)

7.9E-03

2

V$OTX2.01

NNGGATTAANNN

TGGGATTAAAGG

B1_Mm (-22:-33)

3.0E-04

2

V$TTF1.01

NNWSTCAAGYRYWN

CCTCcCAAGTGCTG

B1_Mus1 (-33:-46)

4.6E-03

1

V$LEF1.02

NNNWTCAAAGN

GTCTaCAAAGT

B1_Mm (83:93)

1.4E-02

1

V$PAX6.02

NNAGKKCCAGGNNMG

TGAGTTCCAGGACAG

B1_Mm (93:107)

1.0E-05

2

V$ERR_01

NNTCAAGGTCASNN

GTTCcAGGaCAGCC

B1_Mm (96:109)

3.9E-02

2

V$GRE.01

NNGGTWCNNNNTGTTCTNR

GTaGccCTGGCTGTcCTGG

B1_Mus1 (-100:-118)

1.9E-02

1

V$CP2.02

NWCYGSNNMWNNCTNGNY

CTCTGtATAgCCCTGGCT

B1_Mm (-106:-123)

1.7E-02

1

V$MTATA.01

NNNTWTAAANCNNNNNN

CTCTgTAtAGCCCTGGC

B1_Mm (-107:-123)

4.6E-02

1

V$MEF2.04

NNTGTTACTAAAAATAGAAMNN

AGgGTTtCTctgtATAGccCTG

B1_Mm (-109:-130)

3.4E-02

1

V$RSRFC4.02

ANKCTAWAAATAGMWNN

tTTCTcTgtATAGCcCT

B1_Mm (-110:-126)

4.9E-02

1

V$MEF2.03

NNKWKCTAWAAATAGMNN

GGTTTCTcTgtATAGCCC

B1_Mm (-111:-128)

3.9E-02

1

V$RSRFC4.01

NWKCTAWAAATAGMNN

TTTCTcTgtATAGCCC

B1_Mm (-111:-126)

4.9E-02

1

V$AMEF2.01

NNNNNTAAAAATANCNNN

CTGTCTcgAAAaAACAAA

B1_Mm (129:146)

1.1E-02

2

V$FAST1.01

NNTTGTKKATTGGS

TTTTGTTTtTTcGa

B1_Mm (-134:-147)

3.9E-02

2

V$HFH8.01

YRNATAAACANN

CGAAaAAACAAA

B1_Mm (135:146)

1.1E-02

2

V$XFD2.01

NNWATAAACANNN

CGAAaAAACAAAA

B1_Mm (135:147)

4.5E-02

2

V$HFH1.01

AWATAAACAWTN

gAAaAAACAAaA

B1_Mm (136:147)

2.7E-02

2

V$HFH2.01

RAANAAAYAWTN

GAAAAAACAAaA

B1_Mm (136:147)

2.0E-03

2