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Table 7 Sequence Divergence of Some (A) Chlamydiales-specific vs (B) Broadly-Distributed Proteins

From: BLAST screening of chlamydial genomes to identify signature proteins that are unique for the Chlamydiales, Chlamydiaceae, Chlamydophila and Chlamydia groups of species

A

      

Protein Loci/Identity

C. tra

C. mur

C. pneu

C. cav

C. abo

Protochlam

CT007

316/316 (100%)

273/316 (86%)

184/316 (58%)

185/316 (58%)

183/316 (57%)

48/316 (23%)

CT016

242/242 (100%)

205/242 (84%)

146/246 (59%)

153/245 (62%)

148/245 (60%)

83/246 (33%)

CT017

433/433 (100%)

358/440 (81%)

224/401 (55%)

241/432 (55%)

248/432 (57%)

123/415 (29%)

CT021

247/247 (100%)

184/247 (74%)

102/244 (41%)

115/244 (47%)

108/245 (44%)

73/254 (28%)

CT031

100/100 (100%)

84/100 (84%)

65/100 (65%)

63/100 (63%)

63/100 (63%)

36/95 (37%)

CT038

116/116 (100%)

95/114 (83%)

55/112 (49%)

52/98 (53%)

49/98 (50%)

34/94 (36%)

Average

100%

81.5%

55%

56%

55%

31%

B

      

Protein Loci/Identity

C. tra

C. mur

C. pneu

C. cav

C. abo

Protochlam

CT008 Ribo. HII

300/300 (100%)

257/301 (85%)

186/301 (61%)

185/300 (61%)

185/300 (61%)

139/301 (45%)

CT009 HthTR

152/152 (100%)

133/151 (87%)

105/143 (69%)

101/143 (66%)

105/143 (69%)

47/162 (28%)

CT013 Cyt. Ox. I

446/446 (100%)

406/445 (91%)

317/448 (70%)

325/446 (72%)

328/446 (73%)

195/465 (41%)

CT015 PhoH

434/434 (100%)

394/434 (90%)

314/424 (72%)

339/430 (78%)

338/430 (77%)

218/433 (49%)

CT019 IleRS

1036/1036 (100%)

923/1036 (89%)

715/1043 (68%)

729/1043 (69%)

729/1043 (69%)

575/1038 (55%)

CT022 Ribo. L31

108/108 (100%)

103/108 (95%)

90/109 (81%)

87/208 (80%)

86/108 (79%)

67/117 (57%)

CT034 YtfF

341/341 (100%)

279/341 (81%)

183/338 (53%)

203/338 (59%)

203/339 (59%)

94/281 (27%)

Average

100%

88%

67%

69%

69%

43%

  1. The pair-wise amino acid sequence identity was determined for various chlamydial species for six C. trachomatis proteins that are specific for Chlamydiales (A) and seven other proteins that are broadly distributed in bacteria (B). The numbers in these Tables indicate the length over which the two sequences match each other as well as the % amino acid identity between the two sequences.
  2. The abbreviations in protein names in part (B) are as follows: Ribo. HII, Ribonuclease HII; HthTR, Helix-turn-helix transcriptional regulator; Cyt. Ox. I, Cytochrome oxidase subunit I; PhoH, PhoH-ATPase; IleRS, Isoleucyl tRNA synthetase; Ribo. L31, Ribosomal L31 protein; YtfF, YytF-cationic amino acid transporter.