Figure 2

Alternative splice forms of selected Wnt-components. At top genomic DNA is depicted with all exons. In the middle the cDNA-structure of the normal form is given, the coding region is indicated in yellow, at the bottom the alternative isoform is shown; skips are indicated in red, inserts in blue. On the right side the length in bp is given of the pertinent sequence. For all cases, only the single splice event is shown. Potential other splice sites are neglected. A: CTNNB1(a), B: CTNNB1(b), C: CtBP1, D: GSK-3β, E: Axin-1, F: LRP5