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Table 1 Frequency of upstream AUGs and ORFs.

From: Evidence for conservation and selection of upstream open reading frames suggests probable encoding of bioactive peptides

  Human Mouse
Number of mRNA sequences in initial dataset (1) 16504 11291
Number of mRNA sequences containing > 1 uAUG (2) 9531 6352
Total number of uAUGs (3) 35599 24308
Number of mRNA sequences containing > 1 uORF (4) 4557 2820
Total number of uORFs (5) 8216 5487
Number of mRNA sequences containing > 1 uORF after removal of duplicates (6) 3924 2795
Total number of uORFs after removal of duplicates (7) 7138 5430
Number of mRNA sequences containing > 1 uORF after removal of blast matches (8) 3650 2678
Total number of uORFs after removal of blast matches (9) 6454 5089
  1. Frequency of upstream AUGs and ORFs in human and mouse RefSeq mRNA sequences. Initial dataset refers to all sequences of > 60 nucleotides annotated as 5' UTRs. Numbers in parentheses indicate the corresponding stage in the filtering flowchart (figure 1).