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Table 2 Frequency of downstream AUGs and ORFs.

From: Evidence for conservation and selection of upstream open reading frames suggests probable encoding of bioactive peptides

  Human Mouse
Number of mRNA sequences in initial dataset (1) 21597 14790
Number of mRNA sequences containing > 1 dAUG (2) 19853 14327
Total number of dAUGs (3) 352301 229945
Number of mRNA sequences containing > 1 dORF (4) 16965 11598
Total number of dORFs (5) 85876 55815
Number of mRNA sequences containing > 1 dORF after removal of duplicates (6) 14252 11377
Total number of dORFs after removal of duplicates (7) 69202 54403
Number of mRNA sequences containing > 1 dORF after removal of blast matches (8) 13899 11299
Total number of dORFs after removal of blast matches (9) 65258 52786
  1. Frequency of downstream AUGs and ORFs (dAUGs and dORFs) in human and mouse RefSeq mRNA sequences. Initial dataset refers to all sequences of > 60 nucleotides annotated as 3' UTRs. Numbers in parentheses indicate the corresponding stage in the filtering flowchart (figure 1).