Table 1 Molecular evolution and paralogy of disease genes involved in dominant and recessive diseases at protein level. Average values for mouse and paralogues conservation score for different sets of genes.
From: Differences in the evolutionary history of disease genes affected by dominant or recessive mutations
CS mouse | n | CS paralogues | n | |
|---|---|---|---|---|
Non disease | 0.730 | 16789 | 0.385 | 17962 |
Disease | 0.795 | 1105 | 0.349 | 1108 |
Disease Dominant | 0.810 | 474 | 0.420 | 478 |
Disease Recessive | 0.783 | 631 | 0.295 | 630 |