Predicting candidate genes for human deafness disorders: a bioinformatics approach

BMC Genomics

Table 6 Summary of gene numbers from expression-library filtered analysis.

Condition	Map Location	Interval	Number of Genes	Mouse Synteny/Chromo #	Mouse Genes	Human Cochlear Genes	Mouse Inner ear Genes	Interacting Proteins	Shared Interactors
DFNA7	1q21–q23	18.6 Mb	153	1	161	18	6	15	5
DFNA16	2q24	2.6 Mb	7	2	16	0	0	0	0
DFNA18	3q22	12 Mb	116	6, 9	111	18	4	9	1
DFNA21	6p21	3.5 Mb	9	10	48	0	0	0	0
DFNA23	14q21–q22	8 Mb	79	12	60	7	1	4	0
DFNA25	12q21–24	14 Mb	108	10, 5	102	17	2	11	3
DFNA27	4q12	15 Mb	71	5	97	10	3	7	2
DFNA30	15q25–26	7 Mb	74	7	58	6	1	2	0
DFNA31	6p21.3	7.5 Mb	304	13, 17	385	13	1	8	2
DFNA34	1q44	5 Mb	88	1	23	3	0	1	0
DFNA42	5q31	12 Mb	176	13, 18	153	21	5	16	6
DFNA47	9p21–22	9 Mb	65	4	79	6	1	3	0
DFNB5	14q12	5.5 Mb	18	12	37	2	0	2	0
DFNB13	7q34–36	1.4 Mb	14	6	15	1	0	2	1
DFNB17	7q31	6.5 Mb	26	6	43	3	1	2	1
DFNB19	18p11	2.8 Mb	13	17	11	1	1	1	1
DFNB20	11q25–qter	13.4 Mb	152	9	263	14	1	6	3
DFNB27	2q23–q31	11 Mb	79	2	95	14	3	3	2
DFNB28	22q13	6.5 Mb	146	15	154	15	5	7	3
DFNB32	1p13.3–22.1	16 Mb	74	3, 5	89	13	3	3	3
DFNB33	9q34.3	3 Mb	86	2	54	3	4	2	2
DFNB35	14q24.1–24.3	8.2 Mb	116	12	103	8	4	3	2
DFNB38	6q26–q27	3.4 Mb	5	17	3	1	0	1	1
DFNB39	7q11.22–q21.12	18 Mb	114	5	108	10	2	2	0
DFNB40	22q11.21–12.1	9 Mb	285	5, 10, 16	76	10	4	4	3
Total			2378		2344	214	52	114	41

ISSN: 1471-2164