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Figure 3 | BMC Genomics

Figure 3

From: Genomes of Helicobacter pylori from native Peruvians suggest admixture of ancestral and modern lineages and reveal a western type cag-pathogenicity island

Figure 3

A. (Top) PCR based analysis of whole cag PAI of hsp-Amerind isolates from Peru. Overlapping primers spanning all of the constituent genes (see methods) amplified all the corresponding PCR products in the expected size range as described previously [30]. M indicates molecular weight marker (100 bp ladder). (Bottom) Amino acid signature of cag A (phosphorylation motifs – colored) – characteristic of modern cag A EPIYA (EPIYA C) as observed for all the SJM isolates from Peru. B. Pictorial depiction (right) of different types of cag A-EPIYA motif types prevalent in different H. pylori populations and their distribution in our isolates (boxes on the left).

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