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Table 1 Mucins identified in man, mouse, chicken and puffer fish

From: An inventory of mucin genes in the chicken genome shows that the mucin domain of Muc13 is encoded by multiple exons and that ovomucin is part of a locus of related gel-forming mucins

Mucin Typea Characteristic Pfam domain Chicken Human Mouse F. rubripes
MUC1 TM SEA ? (0/10)d + + ?
MUC2 G VWD + (23/53) + + +b
MUC3 TM SEA   + +?c  
MUC4 TM VWD + (0/23) + +  
MUC5AC G VWD + (8/42) + +  
MUC5B G VWD + (11/37) + +  
MUC6 G VWD + (19/31) + +  
MUC7     +   
MUC10      +  
MUC12 TM SEA   + +?c  
MUC13 TM SEA + (13/24) + + +
MUC14      +  
MUC15 TM    +   
MUC16 TM SEA + (0/16) + +  
MUC17 TM SEA   + +?c  
MUC19 G VWD   + +  
MUC20     + +  
Ovomucin   VWD + (45/45)    
  1. a 'TM' refers to transmembrane domain and 'G' gel-forming mucin
  2. bAll VWD-containing mucins in Fugu rubripes were named Muc2, although the evolutionary relationship of these mucins to the human mucins MUC2/5AC/5B/6 is not clear.
  3. cThe mucin gene cluster in mouse for the Muc3/Muc12/Muc17 mucins is incompletely sequenced. A mouse mucin has been described as Muc3 [42], but is most likely the orthologue of the human MUC17.
  4. dThe numbers within parentheses indicate the number of exons supported by chicken ESTs as compared to the total number of exons. For Muc1, Muc5ac, and Muc16 the indicated total number of exons is a minimum number as the complete gene structure is not known.