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Table 5 Oryzias latipes genes under positive Darwinian selection with significantly lower distance to the human ortholog than other fish species. Duplicated genes are given with rate differences between the two copies according to the relative rate test of Tajima (1993) at the 5% level with one asterisk and at the 1% level with two asterisks.

From: Many genes in fish have species-specific asymmetric rates of molecular evolution

GenBank Acc#

annotation according to human (UniGene)

duplicate rate difference

AJ457222

DNA topoisomerase I

-

AU167343

CLIP-associating protein 1

-

AU167618

Ras-related associated with diabetes

-

AU167923

atrophin-1 interacting protein 1

-

AU176665

TAF6-like RNA polymerase II

-

AU177030

protein inhibitor of activated STAT X isoform beta

-

AU177176

metastasis suppressor 1

-

AU177627

Utrophin

-

AU180234

SNF2 histone linker PHD RING helicase

-

AV668786

AMPK-related protein kinase 5

-

AV670534

hippocampus abundant transcript 1

0.080*

BJ000375

ephrin receptor EphA2

0.149*

BJ003764

mitogen-activated protein kinase kinase kinase kinase 3

-

BJ004731

NICE-4 protein

-

BJ005724

tsJ homolog 1 isoform a

-

BJ007326

transcription factor T

-

BJ007726

G protein-coupled receptor 155

-

BJ008665

transducin-like enhancer protein 4

-

BJ008817

protein kinase C and casein kinase substrate in neurons 2

-

BJ021405

nucleoporin 62 kDa

-

BJ488812

fibulin 6

-

BJ490986

TRAF2 and NCK interacting kinase

-

BJ493563

PDZ domain containing ring finger 1

-

BJ495426

endothelin converting enzyme 1

0.084

BJ501370

DIP2-like protein isoform a

-

BJ517858

microfibrillar-associated protein 1

-

BJ519269

BCL2/adenovirus E1B 19kD interacting protein 2

-

BJ524171

component of oligomeric golgi complex 4

-

BJ527988

UDP-glucose ceramide glucosyltransferase-like 1

-

BJ539899

nuclear phosphoprotein PWP1

-

BJ543391

ribosomal protein L27a

-

BJ704447

pre-B-cell colony enhancing factor 1 isoform a

-

BJ704659

TCDD-inducible poly(ADP-ribose) polymerase

-

BJ706497

ubiquitin specific protease 34

-

BJ713400

neuro-oncological ventral antigen 1 isoform 2

-

BJ717464

thimet oligopeptidase 1

-

BJ724303

dihydrolipoamide S-succinyltransferase

-

BJ728080

myeloid/lymphoid or mixed-lineage leukemia 3

-

BJ728082

chromodomain helicase DNA binding protein 4

-

BJ728281

engulfment and cell motility 1 isoform 1

-

BJ728299

transcription factor AP-2 alpha

-

BJ728451

spermine synthase

-

BJ728665

Rb1-inducible coiled coil protein 1

-

BJ729946

intersectin 1 isoform ITSN-l

-

BJ730543

B-cell lymphoma 6 protein;

-

BJ730756

RE1-silencing transcription factor

-

BJ731205

MLL septin-like fusion

-

BJ733043

T-cell lymphoma invasion and metastasis 1

-

BJ733490

RAD21 homolog

-

BJ733549

SH3-domain binding protein 4

-

BJ734934

serine/threonine kinase 2

-

BJ735209

methylene tetrahydrofolate dehydrogenase 2 precursor

-

BJ735433

Huntingtin

-

BJ736888

bromodomain containing protein 2

-

BJ737071

fibrinogen C domain containing 1

0.061

BJ742416

JM1 protein

-

BJ743130

Moesin

-

BJ746379

microtubule associated serine/threonine kinase-like

-