Comparative evolutionary genomics of the HADH2 gene encoding Aβ-binding alcohol dehydrogenase/17β-hydroxysteroid dehydrogenase type 10 (ABAD/HSD10)

Table 1 Accsession numbers, chromosome location and GC content of HADH2 genes

Species	Accession Number	Chromosome location	Gene length (Kb)	GC_gene	GC_coding
					GC₁	GC₂	GC₃
human (Homo sapiens)	ENSG00000072506	chromosome X (p11.2)	3.11	52	66	46	63
chimpanzee (Pan troglodytes)	ENSPTRG00000021929	chromosome X	3.12	52	66	46	63
orangutan (Pongo Pygmaeus)	^a	-	3.11	52	66	45	63
rhesus monkey (Macaca mulatta)	ENSMMUG00000009296	geneScaffold_500	3.17	51	66	45	65
rat (Rattus norvegicus)	ENSRNOG00000003049	chromosome X	2.45	48	64	44	52
mouse (Mus musculus)	ENSMUSG00000025260	chromosome X	2.56	49	64	44	50
dog (Canis familiaris)^b	ENSCAFG00000016277	chromosome X	2.29	52	66	44	61
cat (Felis catus)^c	^a	-	2.30	51	66	44	60
cow (Bos Taurus)	ENSBTAG00000017779	chromosome X	2.32	52	64	46	62
pig (Sus scrofa)^d	TC220713	-	-	-	66	45	66
opossum (Monodelphis domestica)^e	ENSMODG00000020889	scaffold_255	1.80	55	66	46	64
western clawed frog (Xenopus tropicalis)^f	ENSXETG00000007721/TC2334	scaffold_154	3.17	44	63	43	48
african clawed frog (Xenopus laevis)^d	TC274805	-	-	-	62	44	48
zebrafish (Danio rerio)	ENSDARG00000017781	chromosome 18	9.38	33	62	47	49
Fugu (Takifugu rubripes)^c	SINFRUG00000123807	scaffold_2159	1.81	51	66	47	69
Tetraodon (Tetraodon nigroviridis)	GSTENG00023338001	chromosome 9	1.73	57	67	48	81
fruitfly (Drosophila melanogaster)	CG7113	chromosome X	1.61	51	62	44	83
mosquito (Anopheles gambiae)^c	ENSANGG00000012647	chromosome 2R	0.77	60	67	42	73
honeybee (Apis mellifera)	ENSAPMG00000015843	group11	1.49	18	54	38	12
Caenorhabditis elegans	F01G4.2	chromosome IV	2.50	34	63	43	35
Caenorhabditis briggsae ^c	CBG06017	assembly cb25.fpc0143	1.13	43	61	43	40

^a These gene sequences were manually inferred based on species specific WGS sequences retrieved from a tblastn search to NCBI trace archive: orangutan – ti812046525, ti812049734, ti848517349, ti718725185; cat – ti651599423, ti653340876, ti825822144, ti646417680, ti818302482, ti826254688
^b The gene sequence does not include the 5' UTR sequence
^c The gene sequences does not include the UTR sequences
^d No information available about intronic sequences
^e The gene sequence does not include the first exon, first intron and UTRs sequences
^f The gene sequence does not include the first intron and UTR sequences

ISSN: 1471-2164