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Table 1 Mycelium up-regulated genes identified by in silico ESTs subtraction and cDNA microarray.

From: Cell organisation, sulphur metabolism and ion transport-related genes are differentially expressed in Paracoccidioides brasiliensis mycelium and yeast cells

PbAEST Acession Numbers (GenBank) Annotated function Number of reads P-valuea Fold change Accession Number/Best-hit organism/E-value Functional categories
    M Y     
202 CA582032 1,3-beta-glucosidase* 7 2 0.036942 12.3 AAL09828.1/C. immitis/1.0E-132 Control of cell organization: Cell wall and membrane
2155 CA582352 Peroxisomal membrane protein PEX16 (peroxin-16) 7 0 0.004174 1.4 EAL88469.1/A. fumigatus/3.0E-64  
186 CA583085 HEX* 13 8 0.049272 3.4 EAL91716.1/A. fumigatus/3.0E-66  
2496 CA583518 Iron-sulphur cluster nifU-like protein* 5 1 0.048854 1.7 EAL90111.1/A. fumigatus/8.0E-58 Ion transport
4179 CN245816 Potassium transporter protein* 0 1 -b 5.2 CAA08814.1/N. crassa/4.0E-22  
1420 CN247275 U1 small nuclear ribonucleoprotein 9 1 0.00526 1.6 EAL91268.1/A. fumigatus/1.0E-60 Transcription
1029 CA582332 Methyltransferase 32 1 0.000000 2.1 EAL84975.1/A. fumigatus/1.0E-56 Others
2096 CA581148 Unkown 20 1 0.000006 5.6 -  
514 CA583322 Unkown 15 1 0.000138 23.4 -  
1045 CA581951 Unkown 13 2 0.001769 24 -  
1178 CN247241 Unkown 10 0 0.000535 8.5 -  
1664 CN247289 Unkown 10 3 0.018648 2.5 -  
  1. aFDR = 4,8% and Q-value < 5%.
  2. bNot significant by Audic-Claverie's method.
  3. * Up-regulated genes confirmed by northern blotting.
  4. ** Not assayed by cDNA microarray but confirmed as up-regulated in mycelium by northern blotting.