Figure 4

Function of selected Leu3 target genes. (A) Metabolic pathways in which Leu3 target genes function. Genes that are bound and regulated according to at least one combination of low or high activity expression and low or high ChIP analysis were subjected to GO process analysis, yielding 17 genes with enriched annotations. Gene names shown here are for those genes encoding enzymes directly involved in amino acid biosynthesis. (B) Transcriptional regulatory network involving Leu3. Interactions of Leu3 with other transcription factor genes are inferred from some combination of expression and ChIP experiments as described in the text. Interactions of transcription factors other than Leu3 are inferred from the literature.