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Figure 4 | BMC Genomics

Figure 4

From: Assessment of whole genome amplification-induced bias through high-throughput, massively parallel whole genome sequencing

Figure 4

A & B: Empirical cumulative distribution functions. A. Empirical cumulative distribution function (ECDF) depicting the distributions of counts per bin for various control and amplified populations of Halobacterium species NRC-1 DNA. The ECDF represents the cumulative distribution of the number of counts per bin, reporting the cumulative proportion of bins with counts equal or less than the value on the X axis. The control cumulative fraction (black) is plotted against all WGA approaches; GenomiPhi in blue, Repli-G in orange, PEP in green and DOP in purple. Inset. Generic ECDF of two different distributions (red and blue), the D statistic is shown as black vertical line labelled "D". B as Figure 4A, but derived from Campylobacter jejuni.

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BMC Genomics

ISSN: 1471-2164

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