Figure 5

A & B: Comparison of Halobacterium sequence coverage. Distribution of sequence coverage from unamplified reference, unamplified replicate and whole genome amplified Halobacterium species NRC-1 populations as determined by sequence based karyotyping at 100 base resolution. A. Distribution of the counts per bin (y-axis) across the length of the genome (X axis) of test populations relative to the unamplified reference population. The counts per bin from the unamplified reference population are depicted in black above the X axis, counts from the various test populations are inverted and shown below the X axis. The data from the unamplified replicate population is shown in red, GenomiPhi in blue, Repli-G in orange, PEP in green and DOP in purple. B. Log-log plot of the counts per bin from the unamplified reference population versus the various test populations. The comparison between the reference and the unamplified replicate population is shown in red, GenomiPhi in blue, Repli-G in orange, PEP in green and DOP in purple. A 45 degree black line is shown for comparison.