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Table 4 The top 25 genes exhibiting increased mRNA abundance 2 hours post activation.

From: Development and validation of a bovine macrophage specific cDNA microarray

Clone

E value

Accession No.

Gene Symbol

Gene

Fold Increase

FDRmax

P value

pIL8

0.0

NM_173925

IL8

Interleukin 8

40.00

1.23E-18

4.91E-22

MARC_3BOV_60P17

0.0

NM_174299

CXCL2

Chemokine (C-X-C motif) ligand 2 (GROβ/MIP2A)

38.20

1.25E-15

1.24E-18

C0006019e20

0.0

NM_181015

PRNP

Prion protein

28.13

1.05E-20

2.08E-24

MARC_1BOV_101M3

0.0

NM_174263

CCL20

Chemokine (C-C motif) ligand 20 (MIP3A)

25.81

3.14E-10

3.56E-12

MARC_1BOV_94L3

0.0

NM_174300

CXCL6

Chemokine (C-X-C motif) ligand 6

22.91

1.72E-11

1.23E-13

C0005209b8

6.00E-72

XM_612426

CCRN4L

CCR4 carbon catabolite repression 4-like

20.49

1.64E-11

1.14E-13

C0006018n14

0.0

NM_174006

CCL2

Chemokine (C-C motif) ligand 2 (MCP-1)

19.45

1.32E-07

4.19E-09

C0005204j16

0.0

XM_864683

CXCL3

Chemokine (C-X-C motif) ligand 3 (GROγ/MIP2b)

18.16

1.20E-13

3.40E-16

C0006020d11

0.0

XM_865242

ZFAND2A

Zinc finger, AN1-type domain 2A

17.61

1.10E-14

1.31E-17

C0006011e13

e-179

CK976904

-

EST

16.71

3.10E-08

8.41E-10

C0005208k22

e-167

NM_173198

NR4A3

Nuclear receptor subfamily 4, group A, member 3

15.65

2.39E-12

1.14E-14

C0006020e20

0.0

CB419326

-

EST

14.07

9.10E-12

5.60E-14

MARC_3BOV_36F6

0.0

NM_175827

CCL5

Chemokine (C-C motif) ligand 5 (RANTES)

13.84

2.90E-12

1.47E-14

C0006018g13

0.0

XM_611249

SLCO4A1

Solute carrier organic anion transporter family, member 4A1

13.79

4.62E-10

5.89E-12

MARC_1BOV_72M12

0.0

XM_866821

CXCL10

Chemokine (C-X-C motif) ligand 10 (IP10)

13.71

1.09E-05

6.09E-07

C0005199c13

0.0

AY248754

TNFAIP3

TNF-alpha induced protein 3

13.48

2.34E-08

5.90E-10

C0006015e11

0.0

XM_881561

PMAIP1

Phorbol-12-myristate-13-acetate-induced protein 1

12.99

1.95E-12

8.90E-15

C0005202i8

0.0

XM_583725

APOBEC3A

Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A

12.96

1.20E-13

2.97E-16

MARC_3BOV_120N21

0.0

NM_174028

CSF3

Colony stimulating factor 3 (granulocyte) (G-CSF)

12.76

8.11E-11

7.73E-13

C0006015n15

2.00E-69

NM_002748

MAPK6

Mitogen-activated protein kinase 6 (erk-3)

12.64

8.88E-12

5.11E-14

C0006016h15

0.0

XM_613370

RGS1

Regulator of G-protein signalling 1

12.59

5.10E-09

1.00E-10

C0006013p15

e-158

CB534198

-

EST

12.59

1.93E-11

1.50E-13

C0005202d9

0.0

XM_870158

ANKRD22

Ankyrin repeat domain 22

11.99

6.36E-17

3.79E-20

MARC_1BOV_57B12

0.0

NM_174348

ICAM1

Intercellular adhesion molecule 1 (CD54)

11.40

6.40E-10

9.15E-12

C0005206b23

3.00E-82

NM_001432

EREG

Epiregulin

10.98

1.98E-07

6.61E-09

  1. Summary of the top 25 genes exhibiting increased mRNA abundance 2 hours post activation, including clone name, accession number, e-value and identity of the best BLAST match and average fold change. The P and FDRmax values denote the probability from the moderated t-test and the Benjamini and Hochberg false discovery rate values respectively from the analysis of the resting cell values compared to the average activated sample values (Pre v Post).