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Table 5 The top 25 genes exhibiting decreased mRNA abundance 2 hours post activation.

From: Development and validation of a bovine macrophage specific cDNA microarray

Clone E value Accession No. Gene Symbol Gene Fold Decrease FDRmax P value
C0006018h16 0.0 NM_031483 ITCH Itchy homolog E3 ubiquitin protein ligase -5.36 2.55E-10 2.79E-12
MARC_2BOV_14N13 e-151 XM_582744 IL16 Interleukin 16 -4.94 9.35E-10 1.41E-11
C0006011p15 0.0 NM_003400 XPO1 Exportin 1 -4.11 3.28E-03 4.70E-04
C0006011d04 e-112 NM_000199 SGSH N-sulfoglucosamine sulfohydrolase -4.05 4.14E-05 2.88E-06
C0005202b11 0.0 NM_006565 CTCF CCCTC-binding factor -3.83 9.04E-06 4.90E-07
C0006014p20 0.0 NM_005642 TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa -3.74 7.65E-09 1.61E-10
MARC_1BOV_107K4 0.0 XM_584158 CCR2 Chemokine (C-C motif) receptor 2 -3.70 4.81E-06 2.40E-07
C0005203a5 6.00E-54 NM_032804 C10orf22 Chromosome 10 open reading frame 22 -3.69 2.77E-04 2.68E-05
C0006005d04 0.0 XM_588702 UNG Uracil-DNA glycosylase -3.62 4.24E-10 5.00E-12
C0007385D18 0.0 BM087483 - EST -3.60 2.00E-03 2.63E-04
C0006007o03 e-153 NM_016046 EXOSC1 Exosome component 1 -3.51 6.69E-07 2.57E-08
C0006019m08 0.0 XM_868169 - Hypothetical protein LOC616204 -3.51 8.67E-06 4.67E-07
C0005205c2 2.00E-70 NM_024939 RBM35B RNA binding motif protein 35B -3.50 7.22E-08 2.15E-09
C0005207d22 0.0 NM_013444 UBQLN2 Ubiquilin 2 -3.48 1.36E-08 3.13E-10
C0005198j2 7.00E-58 NM_139014 MAPK14 Mitogen-activated protein kinase 14 (p38) -3.41 1.36E-08 3.15E-10
C0006005h08 0.0 NM_052911 ESCO1 Establishment of cohesion 1 homolog 1 -3.36 9.89E-06 5.48E-07
C0005202l16 4.00E-42 XM_545369 C6orf32 Chromosome 6 open reading frame 32 -3.32 2.43E-10 2.61E-12
MARC_2BOV_105E23 e-119 NM_153425 TRADD TNFRSF1A-associated via death domain -3.18 3.95E-07 1.45E-08
C0006007o20 e-111 NM_001001806 ZFP36L2 Zinc finger protein 36, C3H type-like 2 -3.18 3.22E-09 5.75E-11
C0005209h6 e-108 NM_006163 NFE2 Nuclear factor (erythroid-derived 2), 45kDa -3.13 3.40E-06 3.27E-07
C0006019p19 e-106 XM_868699 TOB2 Transducer of ERBB2, 2 -3.13 8.37E-07 3.31E-08
C0005202g13 0.0 AV594592 - EST -3.11 7.31E-04 8.25E-05
C0005208j1 0.0 CB221804 - EST -3.10 6.65E-05 5.18E-06
C0006012f10 1.00E-67 NM_145037 FAM55C Family with sequence similarity 55, member C -3.08 1.03E-11 6.98E-14
C0005208h20 0.0 CB420023 - EST -3.01 1.67E-05 9.91E-07
  1. Summary of the top 25 genes exhibiting decreased mRNA abundance 2 hours post activation, including clone name, accession number, e-value and identity of the best BLAST match and average fold change. The P and FDRmax values denote the probability from the moderated t-test and the Benjamini and Hochberg false discovery rate values respectively from the analysis of the resting cell values compared to the average activated sample values (Pre v Post).