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Table 6 The top 25 genes exhibiting increased mRNA abundance 16 hours post activation.

From: Development and validation of a bovine macrophage specific cDNA microarray

Clone E value Accession No. Gene Symbol Gene Fold Increase FDRmax P value
pIL8 0.0 NM_173925 IL8 Interleukin 8 60.09 1.23E-18 4.91E-22
MARC_1BOV_94L3 0.0 NM_174300 CXCL6 Chemokine (C-X-C motif) ligand 6 27.46 1.72E-11 1.23E-13
C0006007m23 2.00E-72 XM_868409 DFNA5 Deafness, autosomal dominant 5 25.42 6.52E-13 2.72E-15
MARC_3BOV_60P17 0.0 NM_174299 CXCL2 Chemokine (C-X-C motif) ligand 2 (GROβ/MIP2A) 25.14 1.25E-15 1.24E-18
C0006006k10 0.0 XM_586036 ANKRD37 Ankyrin repeat domain 37 23.35 4.05E-07 1.51E-08
C0006016h15 0.0 XM_613370 RGS1 Regulator of G-protein signalling 1 22.10 5.10E-09 1.00E-10
C0006019g12 e-134 CK965770 - EST 21.24 2.26E-11 1.80E-13
C0006019e20 0.0 NM_181015 PRNP Prion protein 20.34 1.05E-20 2.08E-24
C0006014j10 6.00E-96 NM_000214 JAG1 Jagged 1 18.39 1.81E-08 4.42E-10
C0005208m7 e-110 NM_000785 CYP27B1 Cytochrome P450, family 27, subfamily B, polypeptide 1 18.39 4.10E-09 7.83E-11
C0006007a22 0.0 NM_022154 SLC39A8 Solute carrier family 39 (zinc transporter), member 8 16.01 7.46E-10 1.10E-11
C0005204j16 0.0 XM_864683 CXCL3 Chemokine (C-X-C motif) ligand 3 (GROγ/MIP2b) 15.28 1.20E-13 3.40E-16
MARC_2BOV_43M14 e-132 NM_001124 ADM Adrenomedullin 14.23 1.20E-13 3.00E-16
C0005198l1 e-138 BI975933 - EST 11.26 2.12E-05 1.30E-06
MARC_3BOV_120N21 e-102 NM_172219 CSF3 Colony stimulating factor 3 (granulocyte) (G-CSF) 11.14 8.11E-11 7.73E-13
C0006020e20 0.0 CB419326 - EST 10.79 9.10E-12 5.60E-14
MARC_1BOV_103H23 0.0 XM_586821 IL2RB Interleukin 2 receptor, beta 9.96 3.73E-05 2.52E-06
C0006005p10 e-171 NM_001102 ACTN1 Actinin, alpha 1 9.95 7.22E-08 2.14E-09
C0006020m09 e-131 NM_005726 TSFM Ts translation elongation factor, mitochondrial 9.63 5.24E-11 4.79E-13
C0006012n18 e-101 NM_000362 TIMP3 TIMP metallopeptidase inhibitor 3 9.50 2.71E-05 1.76E-06
C0005202d9 0.0 XM_870158 ANKRD22 Ankyrin repeat domain 22 9.48 6.36E-17 3.79E-20
pIL1B 0.0 NM_000576 IL1B Interleukin 1, beta 9.37 3.16E-13 1.07E-15
C0006020d11 0.0 XM_865242 ZFAND2A Zinc finger, AN1-type domain 2A 9.28 1.10E-14 1.31E-17
C0005208c5 e-100 NM_002575 SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 9.25 3.92E-14 6.22E-17
C0005202i8 0.0 XM_583725 APOBEC3A Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 8.74 1.20E-13 2.97E-16
  1. Summary of the top 25 genes exhibiting increased mRNA abundance 16 hours post activation including clone name, accession number, e-value and identity of the best BLAST match and average fold change. The P and FDRmax values denote the probability from the moderated t-test and the Benjamini and Hochberg false discovery rate values respectively from the analysis of the resting cell values compared to the average activated sample values (Pre v Post).