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Table 7 The top 25 genes exhibiting decreased mRNA abundance 16 hours post activation.

From: Development and validation of a bovine macrophage specific cDNA microarray

Clone

E value

Accession No.

Gene Symbol

Gene

Fold Decrease

FDRmax

P value

C0006017i16

0.0

BM088889

-

EST

-22.29

2.39E-11

1.94E-13

C0005199l3

0.0

BT021551

RNASE4

Ribonuclease, RNase A family, 4

-21.08

1.43E-09

2.33E-11

C0005209g19

-

-

-

Unique singleton

-13.17

5.49E-13

2.07E-15

C0005198n19

0.0

NM_000014

A2M

Apha-2-macroglobulin

-12.22

6.56E-07

2.50E-08

C0006007m24

1.00E-48

NM_174594

RNASE6

Ribonuclease k6

-8.88

9.11E-12

5.79E-14

C0006020f22

0.0

XM_868762

CLEC4A

C-type lectin domain family 4, member A

-8.45

2.80E-06

1.27E-07

C0005202l16

4.00E-42

XM_545369

C6orf32

Chromosome 6 open reading frame 32

-8.21

2.43E-10

2.61E-12

BARC_5BOV_46G22

0.0

NM_001037446

CD59

CD59 antigen

-8.15

2.11E-07

7.20E-09

C0005206d13

4.00E-57

NM_001009567

MRC1L1

Mannose receptor, C type 1-like 1

-8.15

5.55E-10

7.83E-12

C0005198i18

1.00E-34

AY112657

FGL2

Fibrinogen-like 2

-8.04

5.69E-07

2.16E-08

C0006012b04

0.0

DY139256

-

EST

-6.79

8.65E-10

1.29E-11

C0005206a23

e-163

CK954547

-

EST

-6.34

1.27E-06

5.27E-08

C0005920C16

0.0

DN742393

-

EST

-6.12

7.62E-08

2.29E-09

MARC_3BOV_43C11

e-101

NM_172087

TNFSF13

Tumor necrosis factor (ligand) superfamily, member 13 (APRIL)

-5.81

1.51E-08

3.57E-10

C0005201e6

e-100

NM_005923

MAP3K5

Mitogen-activated protein kinase kinase kinase 5

-5.65

5.83E-04

6.40E-05

C0006018f03

2.00E-41

DV230110

-

EST

-5.55

3.13E-06

1.46E-07

C0006005m10

e-121

NM_001031733

CALML4

Calmodulin-like 4

-5.47

2.06E-07

6.98E-09

C0005210k15

0.0

XM_613642

IQGAP2

IQ motif containing GTPase activating protein 2

-5.45

1.58E-07

5.13E-09

C0005199n6

0.0

NM_001033990

SCP2

Sterol carrier protein 2

-5.44

3.32E-09

5.99E-11

C0005209n7

7.00E-95

NM_001386

DPYSL2

Dihydropyrimidinase-like 2

-5.16

8.42E-08

2.58E-09

MARC_2BOV_14N13

e-151

XM_582744

IL16

Interleukin 16

-5.12

9.35E-10

1.41E-11

C0006016k03

e-124

XM_607564

FLI1

Friend leukemia virus integration 1

-4.88

1.90E-05

1.14E-06

C0005209m4

0.0

XM_583952

IL6R

Interleukin 6 receptor

-4.88

2.49E-11

2.08E-13

MARC_2BOV_42H5

0.0

NM_001014945

C1QA

Complement component 1, q subcomponent, alpha

-4.86

8.14E-06

4.32E-07

C0006018i05

0.0

XM_615814

FKBP5

FK506 binding protein 5

-4.65

7.14E-09

1.46E-10

  1. Summary of the top 25 genes exhibiting decreased mRNA abundance 16 hours post activation, including clone name, accession number, e-value and identity of the best BLAST match and average fold change. The P and FDRmax values denote the probability from the moderated t-test and the Benjamini and Hochberg false discovery rate values respectively from the analysis of the resting cell values compared to the average activated sample values (Pre v Post).