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Table 7 The top 25 genes exhibiting decreased mRNA abundance 16 hours post activation.

From: Development and validation of a bovine macrophage specific cDNA microarray

Clone E value Accession No. Gene Symbol Gene Fold Decrease FDRmax P value
C0006017i16 0.0 BM088889 - EST -22.29 2.39E-11 1.94E-13
C0005199l3 0.0 BT021551 RNASE4 Ribonuclease, RNase A family, 4 -21.08 1.43E-09 2.33E-11
C0005209g19 - - - Unique singleton -13.17 5.49E-13 2.07E-15
C0005198n19 0.0 NM_000014 A2M Apha-2-macroglobulin -12.22 6.56E-07 2.50E-08
C0006007m24 1.00E-48 NM_174594 RNASE6 Ribonuclease k6 -8.88 9.11E-12 5.79E-14
C0006020f22 0.0 XM_868762 CLEC4A C-type lectin domain family 4, member A -8.45 2.80E-06 1.27E-07
C0005202l16 4.00E-42 XM_545369 C6orf32 Chromosome 6 open reading frame 32 -8.21 2.43E-10 2.61E-12
BARC_5BOV_46G22 0.0 NM_001037446 CD59 CD59 antigen -8.15 2.11E-07 7.20E-09
C0005206d13 4.00E-57 NM_001009567 MRC1L1 Mannose receptor, C type 1-like 1 -8.15 5.55E-10 7.83E-12
C0005198i18 1.00E-34 AY112657 FGL2 Fibrinogen-like 2 -8.04 5.69E-07 2.16E-08
C0006012b04 0.0 DY139256 - EST -6.79 8.65E-10 1.29E-11
C0005206a23 e-163 CK954547 - EST -6.34 1.27E-06 5.27E-08
C0005920C16 0.0 DN742393 - EST -6.12 7.62E-08 2.29E-09
MARC_3BOV_43C11 e-101 NM_172087 TNFSF13 Tumor necrosis factor (ligand) superfamily, member 13 (APRIL) -5.81 1.51E-08 3.57E-10
C0005201e6 e-100 NM_005923 MAP3K5 Mitogen-activated protein kinase kinase kinase 5 -5.65 5.83E-04 6.40E-05
C0006018f03 2.00E-41 DV230110 - EST -5.55 3.13E-06 1.46E-07
C0006005m10 e-121 NM_001031733 CALML4 Calmodulin-like 4 -5.47 2.06E-07 6.98E-09
C0005210k15 0.0 XM_613642 IQGAP2 IQ motif containing GTPase activating protein 2 -5.45 1.58E-07 5.13E-09
C0005199n6 0.0 NM_001033990 SCP2 Sterol carrier protein 2 -5.44 3.32E-09 5.99E-11
C0005209n7 7.00E-95 NM_001386 DPYSL2 Dihydropyrimidinase-like 2 -5.16 8.42E-08 2.58E-09
MARC_2BOV_14N13 e-151 XM_582744 IL16 Interleukin 16 -5.12 9.35E-10 1.41E-11
C0006016k03 e-124 XM_607564 FLI1 Friend leukemia virus integration 1 -4.88 1.90E-05 1.14E-06
C0005209m4 0.0 XM_583952 IL6R Interleukin 6 receptor -4.88 2.49E-11 2.08E-13
MARC_2BOV_42H5 0.0 NM_001014945 C1QA Complement component 1, q subcomponent, alpha -4.86 8.14E-06 4.32E-07
C0006018i05 0.0 XM_615814 FKBP5 FK506 binding protein 5 -4.65 7.14E-09 1.46E-10
  1. Summary of the top 25 genes exhibiting decreased mRNA abundance 16 hours post activation, including clone name, accession number, e-value and identity of the best BLAST match and average fold change. The P and FDRmax values denote the probability from the moderated t-test and the Benjamini and Hochberg false discovery rate values respectively from the analysis of the resting cell values compared to the average activated sample values (Pre v Post).