| PPIase | Uniprot Acc. # | kDa | Signal Seq. | Predicted Localisation | Domain Architecture |
---|---|---|---|---|---|---|
Cyclophilins | Cyp1 | Q7SF72* | 17.9 | ~ | Cytoplasmic | PPIase only |
 | Cyp2 | Q7SG06 | 19.7 | ~ | Cytoplasmic | PPIase only |
 | Cyp3 | Q7S7Z6* | 22.6 | N-term. | ER | PPIase only |
 | Cyp4 | P10255 | 24.1 | ~ | Mitochondrial | PPIase only |
 | Cyp5 | Q9P3X9 | 40.6 | ~ | Cytoplasmic | N-term. PPIase, C-term. TPR (x3) motifs |
 | Cyp6 | Q7RXA6 | 65.8 | ~ | Cytoplasmic | N-term. U-Box, C-term. PPIase |
 | Cyp7 | Q7SCP8 | 70.6 | ~ | Cytoplasmic | N-term. WD-40 (1x), C-term. PPIase |
 | Cyp8 | Q7RZ18 | 90.8 | ~ | Nuclear | N-term. PPIase, Central RRM |
 | Cwc27 | Q7SBX8 | 60.3 | ~ | Nuclear | N-term. PPIase, C-term. Positively charged |
FKBPs | FKBP1 | Q6M981 | 11.8 | ~ | Cytoplasmic | FKBP (1x) only |
 | FKBP2 | P20080 | 13.0 | ~ | Cytoplasmic | FKBP (1x) only |
 | FKBP3 | O60046 | 22.9 | N-term. | ER | FKBP (1x) only |
 | FKBP4 | Q7SCN0 | 50.8 | ~ | Cytoplasmic | N-term. Negatively charged, C-term. FKBP (1x) |
Parvulins | Par1 | Q7RYY4 | 13.7 | ~ | Nuclear | Rotamase only |
 | Pin1 | Q7RVY7 | 21.2 | ~ | Nuclear | N-term. WW domain, C-term. Rotamase |