MCF-7 time and concentration down-regulated genes | MCF-7 time and concentration up-regulated genes | ||
---|---|---|---|
Biological Process | Probability | Biological Process | Probability |
regulation of actin filament length | 4.9E-06 | water-soluble vitamin metabolism | 3.7E-03 |
actin cytoskeleton organization and biogenesis | 1.8E-04 | sodium\:calcium exchange | 6.2E-03 |
actin filament-based process | 2.4E-04 | pentose-phosphate shunt, oxidative branch | 6.2E-03 |
regulation of actin polymerization and/or depolymerization | 4.0E-04 | glyoxylate cycle | 6.2E-03 |
one-carbon compound metabolism | 4.6E-04 | glyoxylate metabolism | 6.2E-03 |
cell organization and biogenesis | 8.2E-04 | vitamin metabolism | 8.6E-03 |
nucleosome assembly | 9.0E-04 | amino acid transport | 1.2E-02 |
carboxylic acid metabolism | 1.5E-03 | thiamin and derivative metabolism | 1.2E-02 |
organic acid metabolism | 1.6E-03 | embryonic eye morphogenesis | 1.2E-02 |
actin polymerization and/or depolymerization | 2.2E-03 | solute, solute exchange | 1.2E-02 |
amine metabolism | 2.4E-03 | thiamin metabolism | 1.2E-02 |
establishment and/or maintenance of chromatin architecture | 3.2E-03 | internal protein amino acid acetylation | 1.2E-02 |
DNA packaging | 4.3E-03 | eye morphogenesis (sensu Vertebrata) | 1.2E-02 |
chromatin assembly/disassembly | 4.7E-03 | eye morphogenesis (sensu Mammalia) | 1.2E-02 |
amino acid metabolism | 4.7E-03 | isocitrate metabolism | 1.2E-02 |
cytoskeleton organization and biogenesis | 5.8E-03 | amine/polyamine transport | 1.3E-02 |
chromosome organization and biogenesis (sensu Eukarya) | 6.4E-03 | regulation of CDK activity | 1.4E-02 |
muscle maintenance | 6.5E-03 | negative regulation of cell proliferation | 1.6E-02 |
negative regulation of actin filament polymerization | 6.5E-03 | GPI anchor biosynthesis | 1.8E-02 |
anion homeostasis | 6.5E-03 | GPI anchor metabolism | 1.8E-02 |
monovalent inorganic anion homeostasis | 6.5E-03 | regulation of survival gene product activity | 1.8E-02 |
asparagine metabolism | 6.5E-03 | negative regulation of survival gene product activity | 1.8E-02 |
sequestering of actin monomers | 6.5E-03 | G2/M transition of mitotic cell cycle | 1.9E-02 |
asparagine biosynthesis | 6.5E-03 | carboxylic acid transport | 2.1E-02 |
nuclear organization and biogenesis | 6.8E-03 | organic acid transport | 2.1E-02 |
amino acid and derivative metabolism | 7.8E-03 | apoptotic mitochondrial changes | 2.4E-02 |
cell growth | 1.0E-02 | germ-cell development | 2.4E-02 |
myelination | 1.3E-02 | protein amino acid acetylation | 2.4E-02 |
isoleucyl-tRNA aminoacylation | 1.3E-02 | G1/S transition of mitotic cell cycle | 2.5E-02 |
threonyl-tRNA aminoacylation | 1.3E-02 | NADPH metabolism | 3.0E-02 |
regulation of actin filament polymerization | 1.3E-02 | NADPH regeneration | 3.0E-02 |
organelle organization and biogenesis | 1.7E-02 | CTP biosynthesis | 3.0E-02 |
salivary gland morphogenesis | 1.9E-02 | UTP metabolism | 3.0E-02 |
salivary gland development | 1.9E-02 | UTP biosynthesis | 3.0E-02 |
folic acid and derivative biosynthesis | 2.6E-02 | pentose-phosphate shunt | 3.0E-02 |
glycine metabolism | 2.6E-02 | CTP metabolism | 3.0E-02 |
cytoplasm organization and biogenesis | 2.6E-02 | synaptic transmission\, cholinergic | 3.0E-02 |
actin filament polymerization | 3.2E-02 | eye morphogenesis | 3.0E-02 |
folic acid and derivative metabolism | 3.2E-02 | pyrimidine ribonucleoside triphosphate metabolism | 3.0E-02 |
regulation of cell growth | 3.8E-02 | pyrimidine ribonucleoside triphosphate biosynthesis | 3.0E-02 |
aspartate family amino acid biosynthesis | 3.8E-02 | pyrimidine ribonucleotide biosynthesis | 3.6E-02 |
L-serine metabolism | 3.8E-02 | GTP metabolism | 3.6E-02 |
nerve ensheathment | 4.4E-02 | GTP biosynthesis | 3.6E-02 |
negative regulation of cell adhesion | 4.4E-02 | pyrimidine ribonucleotide metabolism | 3.6E-02 |
nerve maturation | 4.4E-02 | nicotinamide metabolism | 3.6E-02 |
glycosphingolipid biosynthesis | 4.4E-02 | pyrimidine nucleoside triphosphate metabolism | 3.6E-02 |
tRNA aminoacylation for protein translation | 4.6E-02 | phosphoinositide biosynthesis | 3.6E-02 |
tRNA aminoacylation | 4.6E-02 | oncogenesis | 3.8E-02 |
amino acid activation | 4.6E-02 | DNA repair | 4.2E-02 |
tRNA modification | 4.7E-02 | covalent chromatin modification | 4.2E-02 |
 |  | phosphoinositide metabolism | 4.2E-02 |
 |  | histone deacetylation | 4.2E-02 |
 |  | pyridine nucleotide metabolism | 4.2E-02 |
 |  | heavy metal sensitivity/resistance | 4.2E-02 |
 |  | nerve-nerve synaptic transmission | 4.2E-02 |
 |  | histone modification | 4.2E-02 |
 |  | aldehyde metabolism | 4.2E-02 |
 |  | protein modification | 4.3E-02 |
 |  | main pathways of carbohydrate metabolism | 4.5E-02 |
 |  | obsolete biological process | 4.7E-02 |
 |  | prostanoid metabolism | 4.8E-02 |
 |  | embryonic development (sensu Vertebrata) | 4.8E-02 |
 |  | lipoprotein biosynthesis | 4.8E-02 |
 |  | insulin receptor signaling pathway | 4.8E-02 |
 |  | prostaglandin metabolism | 4.8E-02 |
 |  | embryonic development (sensu Mammalia) | 4.8E-02 |
 |  | protein lipidation | 4.8E-02 |