Table 4 Biological processes significantly affected by BaP in both MCF-7 and HepG2 cells
Time and concentration down-regulated genes | Time and concentration up-regulated genes |
|---|---|
nucleosome assembly | G2/M transition of mitotic cell cycle |
establishment and or maintenance of chromatin architecture | heavy metal sensitivity/resistance |
DNA packaging | nerve-nerve synaptic transmission |
chromosome organization and biogenesis (sensu Eukarya) | obsolete biological process |
nuclear organization and biogenesis | oncogenesis |
chromatin assembly/disassembly | prostaglandin metabolism |
| Â | prostanoid metabolism |
| Â | synaptic transmission, cholinergic |