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Table 4 Biological processes significantly affected by BaP in both MCF-7 and HepG2 cells

From: Time- and concentration-dependent changes in gene expression induced by benzo(a)pyrene in two human cell lines, MCF-7 and HepG2

Time and concentration down-regulated genes Time and concentration up-regulated genes
nucleosome assembly G2/M transition of mitotic cell cycle
establishment and or maintenance of chromatin architecture heavy metal sensitivity/resistance
DNA packaging nerve-nerve synaptic transmission
chromosome organization and biogenesis (sensu Eukarya) obsolete biological process
nuclear organization and biogenesis oncogenesis
chromatin assembly/disassembly prostaglandin metabolism
  prostanoid metabolism
  synaptic transmission, cholinergic