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Table 7 Mean percentages of the MCF-7 and HepG2 cell cycle parameters after 2.5 μM BaP treatment versus control

From: Time- and concentration-dependent changes in gene expression induced by benzo(a)pyrene in two human cell lines, MCF-7 and HepG2

MCF-7
  % G1 % S % G2
Time (h) DMSO BaP DMSO BaP DMSO BaP
24 66.2 63.8 24.8 29.1 9 7.2
48 74.3 75.1 12.6 18.8 13.3 6.2
72 75.5 81.1 14.6 13.7 10 5.2
HepG2
  % G1 % S % G2
Time (h) DMSO BaP DMSO BaP DMSO BaP
24 73.7 63.2 15.8 27 10.6 9.9
48 74.4 70.4 13 19.4 12.7 10.3
72 76.2 71.5 14.3 13.4 9.6 15.2
  1. The values are representative of two independent experiments for which the standard deviation was never greater than 5%. Bold values indicate a significant difference (p < 0.05) between the BaP- and DMSO-treated cells.