Identification of novel regulators in T-cell differentiation of aplastic anemia patients

BMC Genomics

Table 1 Patients' characteristics.

patient	age/sex	diagnosis	PNH-clone	source of sample	pre-therapy sample	post-therapy sample	pool
1	19/F	SAA	n	PB BM	y y	n n	I I
2	57/M	vSAA	n	PB BM	y y	n n	I I
3	40/F	SAA	n	PB BM	y y	n n	I I
4	70/F	SAA	n	PB BM	y y	n n	I I
5	64/M	SAA	n	PB BM	y y	y y	IIa/IIb IIa/IIb
6	70/F	vSAA	n	PB BM	y y	y y	IIa/IIb IIa/IIb

Abbreviations: F = female; M = male; (v)SAA = (very) severe aplastic anemia; n = no; y = yes; PB = peripheral blood; BM = bone marrow; I = pool I at initial presentation (n = 4); IIa = pool II at initial presentation (n = 2); IIb = pool II in hematological remission (n = 2). Disease classification was performed according to the International Study of Aplastic Anemia and Agranulocytosis [45].

ISSN: 1471-2164