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Table 4 Criteria for determination of the true positives (TP), false negatives (FN), false positives (FP) and true negatives (TN) for the microarray results.

From: Novel design and controls for focused DNA microarrays: applications in quality assurance/control and normalization for the Health Canada ToxArray™

 

Microarray Result using the Fs-test

 

Positive

Negative

Overall Treatment Effect

FDR p-value < 0.05

FDR p-value > 0.05

 

AND

OR

Pairwise Comparison with Control*

FDR p-value < 0.05

FDR p-value > 0.05

RT PCR Result

  

p-value < 0.05 (differentially expressed)

TP

FN

p-value > 0.05 (no change)

FP

TN

  1. * comparison of individual doses against the control