Schematic illustration of mRNA expression levels in TGFβ-treated T84 epithelial cells compared to control cell culture. Results are from three separate experiments. In TGFβ-treated cells the expressions of EGFR, PI3K, c-myc and GRB in the Receptor tyrosine kinase (RTK) pathway were decreased. In the TGFβ signaling pathway the expression of TFDP1 and E2F4/5 were decreased, TGIF increased and c-myc as well as IDs decreased. In the TGFβ-treated cells transcription of β-catenin was decreased in the wnt signaling pathway, the wnt+-route was down-regulated, as indicated by down-regulation of c-myc and cyclin D2. The red indicates up-regulation in mRNA expression in a gene with high expression level; pink indicates up-regulation in gene with a low expression level. Dark green indicates a significant down-regulation in a gene which has high expression level; light green indicates down-regulation in a gene with low expression level; dark grey indicates a high level of expression with no change, light grey no change with low concentration expression. White indicates absence from the filter.