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Table 3 Summary of qRT-PCR analysis of the selected genes from the C-AD library

From: Novel subtractive transcription-based amplification of mRNA (STAR) method and its application in search of rare and differentially expressed genes in AD brains

Name Acc # Gene Description % Down Abundance relative to β-actin*
  AF498312 integrin-linked kinase1 (ILK) 29% 19.00%
ANK2 NM_020977 ankyrin2, transcript varient 2 no change 11.00%
GABRB3 CR749803 Gamma-aminobutyric acid A receptor, beta 3 no change 98.00%
UBE2B NM_003337 ubiquitin-conjugating enzyme E2B 45% 33.00%
  AY339422 NADH dehydrogenase sububit 3 30% 475.00%
TPI1 BC017917 triosephosphate isomerase 41% 208.00%
BCAS1 NM_003657 breast carcinoma sequence 1 20% 71.00%
E46L AK095309 Ataxin-10 no change 58.00%
SCA1 NM_000332 spinocerebellar ataxia 1 68% 3.00%
DEAF1 BC053322 transcriptional regulator protein, suppressin 24% 7.00%
HLF M95585 hepatic leukemia factor(HLF) no change 0.70%
CKIP-1 BC010149 TNF intracellular domain-interacting protein 35% 2.00%
SNCA NM_000345 synuclein, alpha SNCA 68% 0.20%
CRI1 AL357456 CREBP/EP300 inhibitory protein 1or RBP21 19% 170.00%
SYT4 BC036538 synaptotagmin IV 58% 74.60%
ARF6 BC030291 ADP-ribosylation factor 6, Arp6 59% 0.82%
PRKCE BC054052 protein kinase C, epsilonY 15% 16.90%
  BC000143 ELMO2 engulfment and cell motility 2 55% 0.07%
SV2A BC045111 synaptic vesicle glycoprotein 2A 19% 2.00%
RELN NM_005045 reelin 82% 1.20%
  BC042904 hypothetical protein DKFZp564A176 15% 22.20%
  NM_152722 hypothetical protein FLJ25530 no change 225.00%
  AK056024 EST 49% 10.60%
  DR005162 EST 21% 1163.00%
  AL162511 genomic DNA 49% 26.00%
  AC096861 genomic DNA 19% 16.00%
  AC145098 genomic DNA 41% 12.00%
  AL590482 genomic DNA 86% 0.150%
  AL121908 genomic DNA 18% 0.0050%
  AL513318 genomic DNA 47% 0.0002%
  AC099787 genomic DNA 100% 0.0012%
  AL354884 genomic DNA 100% 0.0012%
  AC119800 genomic DNA 50% 0.0003%
  AC092631 genomic DNA 40% 0.0002%
  AL138753 genomic DNA 74% 0.0002%
  AL356608 genomic DNA 76% 0.0020%
  AC106856 genomic DNA 17% 0.0001%
  AC012071 genomic DNA no change 0.0290%
  AC112717 genomic DNA 39% 0.0019%
  AP002803 genomic DNA 64% 0.0140%
  AL158212 genomic DNA no change 0.0002%
  1. * Abundance relative to β-actin was calculated using a relative quantitation formula : 2-ΔCt x%, where ΔCt is the qRT-PCR cycle number of target gene minus the qRT-PCR cycle number of β-actin at threshold in the same round of qRT-PCR experiment using cDNA from control brains.