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Figure 6 | BMC Genomics

Figure 6

From: The repertoire of olfactory C family G protein-coupled receptors in zebrafish: candidate chemosensory receptors for amino acids

Figure 6

Amino acid conservation and selective pressure displayed on a structural model of the OlfC N-terminal ligand-binding domain. Percent identity (a, c, e) and inferred selective pressure (b, d, f) for the zebrafish OlfC family is displayed on a structural model of OlfCa1 [28]. The extracellular N-terminal domain (a, b) is represented by a ribbon. The inner, ligand-binding faces of lobe 1 (c, d) and lobe 2 (e, f) are shown as surface representations. Bound glutamate – the cognate ligand for OlfCa1 [28] – is shown docked in the binding pocket with the alpha carbon and proximal pocket oriented to the left and distal pocket to the right. Residues are colored by percent identity, from 2% (red) to 100% (blue) (a, c, e) or by selective pressure (positive selection shown in red (p < 0.1) or orange (p < 0.2), neutral selection in white, and negative selection in blue-green (p < 0.2) or blue (p < 0.1) (b, d, f).

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