Skip to main content

Table 1 Proportions of Single- and Double-Strand Damage Produced by γ-Radiation and Enediynes

From: The DNA-damage signature in Saccharomyces cerevisiae is associated with single-strand breaks in DNA

Agent

Ratio of direct single- to double-strand breaks

Ratio of single- to double-strand deoxyribose oxidation events

γ-Radiation

35–100:1a

35–100:1a

Esperamicin A1

24:1b

3.4:1b

Neocarzinostatin

6:1c

2.2:1c

Calicheamicin-γ1I

1:1d

1:24d

  1. a Reference [25, 26]
  2. b Reference [29]
  3. c Reference [30]
  4. d Reference [12, 31]