Figure 2

Comparison of EFICAz predictions with KEGG annotations. Comparison of EFICAz predictions with KEGG annotations from the Genes database of March 5, 2005, Release 33.0+/03–5 (A-B) and of March 7, 2006, Release 37.0+/03–07 (C-D). We analyze two levels of enzyme function description: four-field EC numbers (A, C) and three-field EC numbers (B, D). For all, archaeal, bacterial and eukaryotic genomes we plot the average percentage of enzymatic proteins per genome whose EFICAz-inferred and KEGG-provided annotations at the specified level of detail agree (green columns) or disagree (red columns), and whose enzyme function annotation at the specified level of detail is only provided by EFICAz (blue columns) or by KEGG (yellow columns). The numeric values inserted in each stacked column are the corresponding average percentage of enzymatic proteins per genome +/- the standard deviation.