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Figure 4 | BMC Genomics

Figure 4

From: Unsupervised clustering of gene expression data points at hypoxia as possible trigger for metabolic syndrome

Figure 4

A Three-dimensional plot of the FOREL clusters from Mootha et al. data set in relationship to Body Mass Index (BMI), total oxygen capacity (VO2max) and insulin sensitivity (M-value). Members of cluster 3, occupying the extreme end of the variation spectrum and two singletons (both non-diabetic) are the most insulin sensitive. Some non-diabetic phenotypes are found in clusters characterized by high risk factors (↓M-value, ↑BMI) particularly cluster 4. Conversely, there is only one subject with IGT in cluster 3. On this plot clusters are represented by corresponding centroids.

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BMC Genomics

ISSN: 1471-2164

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