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Table 1 Representation of different function and location categories of genes in the different groups of secretion stress related genes of S. cerevisiae. Number of S. cerevisiae genes belonging to selected function and location categories within the different groups of secretion stress related genes distinguished in this article. The groups of differentially regulated genes: "c oreUPR", "UPR Dependent Up "UPR Dependent Down", UPR Independent Up" and "UPR Independent Down", are defined in Materials and methods of this study and "UPR by Travers & al. 2000" (UPR regulated genes) are as described by [2], and "Homologues of T. reesei secretion stress ORFs" (numbers of ORFs corresponding to ESTs represented in the cDNA subtraction library and cDNA-AFLP analysis in this study). Category assignments are from CYGD functional or localization categories [51].

From: Common features and interesting differences in transcriptional responses to secretion stress in the fungi Trichoderma reesei and Saccharomyces cerevisiae

Topic Category cUPR UPR Dependent UP UPR Dependent DOWN Not UPR Dependent UP Not UPR Dependent DOWN UPR by Travers & al. 2000 Homologues of T. reesei ER stress ORFs S. cerevisiae genome
Protein secretion related Cellular export and secretion    2 11 3 3 7 76
  Protein fate 23 30 25 137 65 95 62 1130
  Lipid, fattyacid and isoprenoid metabolism 6 10 5 33 18 28 16 271
  Vacuolar transport 2 2 4 26 9 10 11 152
  Vesicular transport 8 5 3 23 7 27 20 197
  Biogenesis of cellular componentsCell wall 2 8 4 21 11 21 16 212
  % of Protein secretion related genes in the group 63% 31% 20% 34% 16% 38% 39% 26%
Transcription related Transcriptional control 1 23 8 44 33 26 23 491
  Transcription 3 35 19 69 140 48 31 1060
  % of Transcription related genes in the group 7% 26% 13% 12% 23% 13% 14% 17%
Outside of cell Extracellular    1 2 9 5 5 50
  Cellwall     2 5 1 3 40
  % of genes Outside of cell in the group 0% 0% 1% 1% 2% 1% 2% 1%
Ribosome biogenesis   2 3   130 3 20 301
Histones        3 8
% of Unclassifed genes in the group 20% 21% 40% 27% 17% 27% 9% 32%
Total number of genes in the group 46 135 155 592 603 381 249 6335