Table 1 Representation of different function and location categories of genes in the different groups of secretion stress related genes of S. cerevisiae. Number of S. cerevisiae genes belonging to selected function and location categories within the different groups of secretion stress related genes distinguished in this article. The groups of differentially regulated genes: "c oreUPR", "UPR Dependent Up "UPR Dependent Down", UPR Independent Up" and "UPR Independent Down", are defined in Materials and methods of this study and "UPR by Travers & al. 2000" (UPR regulated genes) are as described by [2], and "Homologues of T. reesei secretion stress ORFs" (numbers of ORFs corresponding to ESTs represented in the cDNA subtraction library and cDNA-AFLP analysis in this study). Category assignments are from CYGD functional or localization categories [51].

Protein secretion related

2

11

3

3

7

76

23

30

25

137

65

95

62

1130

6

10

5

33

18

28

16

271

2

2

4

26

9

10

11

152

8

5

3

23

7

27

20

197

2

8

4

21

11

21

16

212

63%

31%

20%

34%

16%

38%

39%

26%

Transcription related

1

23

8

44

33

26

23

491

3

35

19

69

140

48

31

1060

7%

26%

13%

12%

23%

13%

14%

17%

Outside of cell

1

2

9

5

5

50

2

5

1

3

40

0%

0%

1%

1%

2%

1%

2%

1%

2

3

130

3

20

301

3

8

20%

21%

40%

27%

17%

27%

9%

32%

46

135

155

592

603

381

249

6335