Figure 2

(A) Whole genome karyogram of the H2087 lung adenocarcinoma cell line profiled on the SMRT array using the May 2004 genomic build. For each chromosome, there is a ratio plot associated with plotting the log₂ ratio of the genomic element vs. the position of the element on the chromosome. The log₂ ratio of the data point is calculated against a normal reference where positive ratios represent increased content and negative ratios represent decreased content in the tumor compared to the normal. (B) The first level of zoom to view a particular chromosome, in this case, chromosome 8. (C) 32X zoom into the amplicon at chromosome band 8q24.21. (D) The ability to link out to biological databases such as NCBI MIM, UCSC Genome Browser, NCBI Gene and NCBI PubMed with a gene of interest.