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Figure 5 | BMC Genomics

Figure 5

From: SIGMA: A System for Integrative Genomic Microarray Analysis of Cancer Genomes

Figure 5

Integration of genomic and epigenetic profiles of the H1395 lung cancer cell line. (A) The genomic profile of H1395 is represented by a moving average spline of the data points. (B) Similarly, the epigenetic profile represents a residual plot of the tumor cell line subtracting the matching blood lymphocyte profile (BL1395), with a moving average spline representing the data points. The moving average was done at 1 MB intervals at increments of 200 kb for both profiles. Specifically, chromosomal region 1q21.3 is highlighted illustrating a region of both copy number increase and hypomethylation.

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