Table 2 Keywords from gene annotations used to identify virulence and virulence-associated genes, and assign functional categories
From: Comparative genomics profiling of clinical isolates of Aeromonas salmonicida using DNA microarrays
Keyworda | Functional category | Relevance |
|---|---|---|
Aerolysin | Toxin | known virulence protein |
antibiotic | Antibiotic resistance | antibiotic resistance/susceptibility |
capsule | CHO/Surface factors | capsule biosynthesis/transport |
catalase | Flagella/pilin; OMP | catalase/peroxidases |
chemotax | IC protect; Toxin | chemotaxis proteins |
chitin | Other; Toxin | chitinase |
cpa | Flagella/pilin | pilus assembly complex |
dismutase | IC protect | superoxide dismutase |
extracel | Other | extracellular proteins |
ferr | Iron systems; Transport; | ferredoxins, ferric transport |
fimb | Flagella/pilin | fimbrial proteins |
flag | Flagella/pilin | flagellar proteins |
glycosyl | CHO/Surface factors | glycosyl transferases |
hemolysin | Toxin | hemolysin/aerolysin |
invas | OMP | invasions or invasion/adhesion |
iron | Iron systems; Transport | iron transport/binding |
Laf | Flagella/pilin | Vibrio parahaemolyticus chemotaxis protein |
Lfg | Flagella/pilin | V. parahaemolyticus flagellar hook protein |
lip | CHO/Surface factors | lipid/lipoprotein |
macrophage | IC protect | macrophage toxins |
membrane | OMP | outer/inner membrane proteins |
OMP | OMP | outer membrane proteins |
penicillin | Antibiotic resistance | penicillin resistance |
peroxid | IC protect ; Toxin | peroxidase |
pil | Flagella/pilin | pilin/pilus assembly protein |
plasmid | Plasmid | plasmid-encoded |
polymer | Sigma | DNA polymerase/Sigma factor |
porin | OMP | outer membrane porin protein |
protease | Other; Toxin | proteases |
pseudopilin | Secretion | part of Type II secretion system |
pul | Flagella/pilin | part of Type II secretion system |
quorum | Other | quorum sensing proteins |
receptor | OMP | membrane receptor proteins |
resistance | Antibiotic resistance | antibiotic resistance |
RTX | Toxin | RTX toxin (hemolysin) |
secret | Secretion | secretion systems/secretory proteins |
sial | CHO/Surface factors; Other; | sialic acid transport/synthetase |
siderophore | OMP | siderophore receptor |
sigma | Sigma | sigma factor |
SOD | IC protect | superoxide dismutase |
superoxide | IC protect | superoxide dismutase |
Tad | Flagella/pilin | Vibrio spp. pilus assembly protein |
tap | Other; Transport | ABC transporter/ATP-binding protein |
toxin | Toxin | toxin genes |
transferase | CHO/Surface factors; Other | glycosyl and other transferases |
transport | Transport | transport proteins |
transpos | Transposon | transposases |
usher | Flagella/pilin | chaperone/usher type fimbriae |
Yop | Secretion | Type III Secretion system gene in Yersinia spp. |