Skip to main content
Figure 3 | BMC Genomics

Figure 3

From: Application of DETECTER, an evolutionary genomic tool to analyze genetic variation, to the cystic fibrosis gene family

Figure 3

Frequencies of amino acids lost and gained through missense mutations of the CFTR protein. A, Observed frequencies of native CFTR amino acids lost through phenotypic missense mutations. B, Same as A but normalized for the particular frequencies of amino acids present in the membrane-spanning domains. C, Observed frequencies of non-native amino acids gained through phenotypic missense mutations from the CFTR mutation database.

Back to article page