(A). Identification of minimal combination of SNPs for maximal prediction value of metabolic expression level of DHEA using leave one out cross validation analysis: women with DHEA_SO4 level>92.6 pmol/l vs women with DHEA_SO4 levels<92.6 pmol/l (p < 0.042). Frequency distribution of the genotypes at each locus: Blue – common homozygous genotype, green – heterozygous, yellow – rare homozygous genotype for each locus (row) and each person (column). Columns labeled by '|' correspond to samples with estrone level < 92.6, columns labeled by '-' correspond to sample with estrone level > 92.6 pmol/l. (B). Stacked diagrams of frequency distribution of the genotypes at each locus.