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Table 2 Correlation between metabolic levels of estradiol and its precursors in the plasma of healthy post-menopausal women. DHEA, dihydroepiandrostenedione, DHEA-SO4, dihydroepiandrostenedione sulfate, androstenedione, testosterone, E1, estrone, E2, estradiol, E1S, estrone- sulphate.

From: Multilocus analysis of SNP and metabolic data within a given pathway

Metabolite

DHEA

DHEA-SO4

Androstenedione

Testosterone

E1

E2

E1S

DHEA

1

      

DNEA-SO4

0.578 p < 0.001

1

     

Androstenedione

0.494 p < 0.001

0.606 p < 0.0001

l

    

Testosterone

NS

NS

0.321 p < 0.001

1

   

E1

0.201 p < 0.034

0.285 p < 0.002

0.217 p < 0.021

NS

1

  

E2

NS

NS

NS

NS

0.873 p < 0.0001

1

 

E1S

NS

NS

NS

NS

0.776 p < 0.0001

0.795 p < 0.0001

1