Figure 7

Structural classification of the Epc-N domain. (a) Results from submitting canonical Epc-N domain sequences (those lacking the PZPM) to the Polish metaserver [52] for tertiary structure analysis. A 3D-Jury score of 50 or greater is considered a significant match. The top three matches for the highest scoring sequences are shown. The subfamily I Epc-N domain from O. sativa NP_914427 produced a significant match to the colicin IM7 protein, a right-handed orthogonal four-helix bundle. Note that while considered statistically below threshold, all of the other top three candidates from the highest scoring sequences were matched to right-handed four-helix bundles. (b) A metaserver-generated alignment between the Epc-N domain of NP_914427 and the matched colicin IM7 structure PDB 1AYI. (c) Structural diagrams.