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Table 3 Nucleotide composition of T. cruzi maxicircle regions

From: Trypanosoma cruzi mitochondrial maxicircles display species- and strain-specific variation and a conserved element in the non-coding region

 

Coding Region

Non-coding Region

Overall

 

CLB

Esmo

Tb

Lt

CLB

Esmo

Tb

Lt

CLB

Esmo

Tb

Lt

% A

38

37

37

35

46

52

59

52

39

40

44

38

% C

11

11

10

10

12

14

9

9

11

11

9

10

% G

15

15

16

13

10

6

8

6

14

13

13

12

% T

37

37

37

43

33

28

24

33

36

36

34

41

% A+T

74

74

74

77

79

80

83

85

75

76

78

79

% G+C

26

26

26

23

21

20

17

15

25

24

22

21

AT skew

0.01

-0.01

0.00

-0.10

0.17

0.30

0.43

0.23

0.04

0.04

0.14

-0.03

GC skew

0.15

0.16

0.24

0.15

-0.08

-0.38

-0.02

-0.17

0.10

0.05

0.19

0.10

  1. Coding region region is defined as the contiguous nucleotide sequence of the maxicircle consensus from the start of 12S rRNA through the end of the ND5 gene including intergenic regions, as defined for T. cruzi in Table 1. CLB, Esmo, Tb, and Lt represent T. cruzi CL Brener strain, T. cruzi Esmeraldo strain, T. brucei maxicircle coding sequence [GenBank:M94286] and variant region sequence [GenBank:Z15118], and L. tarentolae maxicircle sequence [GenBank:M10126]