Figure 2

Hierarchical clustering of the differentially regulated gene lists for A) temporal and B) dose-response microarray studies in mouse hepatoma Hepa1c1c7 cells. The results illustrate time and dose-dependent clustering patterns. From the A) temporal results, the early (2 hr and 4 hr), intermediate (8 hr and 12 hr) and late (24 hr and 48 hr) time points cluster separately while the 1 hr time point clusters alone. Results from the B) dose-response show that highest doses clustered together, while the remaining doses branched out in a dose-dependent manner