Comparative genomics of the syndecans defines an ancestral genomic context associated with matrilins in vertebrates

Table 2 Sequence conservation of representative invertebrate, fish and amphibian syndecans.

Organism	Human-S1	Human-S2	Human-S3	Human-S4
C. savignyi	0.229	0.201	0.219	0.170
A. crassispina	0.190	0.176	-	0.131
D. melanogaster	0.204	0.192	0.179	0.175
C. elegans	0.182	0.150	-	0.112
T. nigroviridis, sdc2	0.230	0.260	0.180	0.190
T. nigroviridis, sdc3	0.241	0.301	0.335	0.206
T. nigroviridis, sdc4	0.210	0.240	0.187	0.292
X. laevis, sdc1	0.363	0.207	0.267	0.170
X. laevis, sdc2	0.224	0.485	0.222	0.247
X. laevis, sdc3	0.260	0.238	0.554	0.196

Amino acid sequences of human syndecans were used to conduct BlastP searches against the Uniprot database. Conservation scores of relevant retrieved hits (representative of invertebrate, urochordate, fish and amphibian) were then calculated [92]. Dashes indicate searches for which no hit with syndecan-3 was retrieved.

ISSN: 1471-2164