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Table 1 Overview of the EST-based data mining strategy. Screening for differentially expressed genes between normal and cancer tissues. EST counts in each analytical step. Total number of EST clusters in each class (upregulated, downregulated, tumor-specific or absent in tumors) was determined after Bonferroni corrected exact Fisher test.

From: Bioinformatic screening of human ESTs for differentially expressed genes in normal and tumor tissues

Total RNA (Ensembl) ~ 31,800
Total ESTs (after clustering) ~ 3.3 106
Total clusters 26,601
Total up-regulated EST clusters 227
Total down-regulated EST clusters 473
Total EST clusters specific to tumors 173
Total EST clusters absent in tumors 308