Table 1 Overview of the EST-based data mining strategy. Screening for differentially expressed genes between normal and cancer tissues. EST counts in each analytical step. Total number of EST clusters in each class (upregulated, downregulated, tumor-specific or absent in tumors) was determined after Bonferroni corrected exact Fisher test.
From: Bioinformatic screening of human ESTs for differentially expressed genes in normal and tumor tissues
Total RNA (Ensembl) | ~ 31,800 |
Total ESTs (after clustering) | ~ 3.3 106 |
Total clusters | 26,601 |
Total up-regulated EST clusters | 227 |
Total down-regulated EST clusters | 473 |
Total EST clusters specific to tumors | 173 |
Total EST clusters absent in tumors | 308 |