Figure 4
The conserved plastic PrP region compared with Shos. White letters on black background, conserved amino acids; bold, similar amino acids. X indicates residue in the highly conserved potential transmembrane region. In the consensus line: capital letters, conserved amino acids; +, conserved basic residues; *, conserved polar residues; !, conserved hydrophobic residues. Bt, Bos taurus; Cf, Canis familiaris; Cj, Callithrix jacchus; Cp, Cavia porcellus; Hs, Homo sapiens; Mm, Mus musculus; Mt, Macaca mulatta; Oc, Oryctolagus cuniculus; Ppa, Pongo pygmaeus abelii; Pt, Pan troglodytes; Rn, Rattus norvegicus. *, sequence annotated in this study.