From: Genomics of glycopeptidolipid biosynthesis in Mycobacterium abscessus and M. chelonae
M. smegmatis | M. abscessus | M. chelonae | ||||
---|---|---|---|---|---|---|
Gene | Gene n° | Proposed function(a) | Gene n° | %(b) | Gene n° | %(b) |
mmpS4 | MSMEG0373 | Membrane associated. Interaction with Pks, ° | ma4117c | 78 | mc1618 | 74 |
mmpL4a | MSMEG0374 | Membrane associated. Interaction with Pks, ° | ma 4116c | 78 | mc1619 | 77 |
mmpL4b | MSMEG0375 | Membrane associated. Interaction with Pks, ° | ma4115c | 76 | mc1620 | 75 |
Rv1174 | MSMEG0376 | None | ma4114 | 48 | mc1621c | 48 |
rmlA | MSMEG0377 | Alpha-D-hexose-1-phosphate-thymidylyl-transferase (EC 2.7.7.24), ° | ma4113 | 85 | mc1622c | 85 |
gtf3 | MSMEG0378 | D-Rhamnose rhamnosyltransferase, + | ma4112c | 49 | mc1623 | 71 |
rmlB | MSMEG0379 | UDP-hexose 4-epimerase, ° | ma4111c | 77 | mc1624 | 78 |
rmt2 | MSMEG0380 | Rhamnose 2-O-methyltransferase, + | ma4109c | 72 | mc1626 | 70 |
rmt4 | MSMEG0381 | Rhamnose 4-O-methyltransferase, + | ma4108c | 83 | mc1627 | 83 |
gtf1 | MSMEG0382 | D-allo-threonine 6-deoxytalosyltransferase, + | ma4107c | 76 | mc1628 | 77 |
atf | MSMEG0383 | Integral membrane protein. 6-deoxytalose 3,4-O-acetyltransferase, + | ma4106c(c) | 72 | mc1629(c) | 76 |
 |  |  | ma4110c(d) | 59 | mc1625(d) | 60 |
rmt3 | MSMEG0384 | Rhamnose 3-O-methyltransferase, + | ma4105c | 81 | mc1630 | 82 |
gtf | MSMEG0385 | L-alaninol rhamnosyltransferase, + | ma4104 | 67 | mc1631c | 72 |
fmt | MSMEG0386 | Fatty acid O-methyltransferase, + | ma4103c | 67 | mc1632 | 62 |
mbtH | MSMEG0387 | None | ma4100c | 89 | mc1635 | 89 |
mps1 | MSMEG0390 | Non-ribosomal protein synthase. Synthesis of the dipeptide, +° | ma4099c | 70 | mc1636 | 70 |
mps2 | MSMEG0392 | Non-ribosomal protein synthase. Synthesis of the amino acid alcohol, +° | ma4098c | 71 | mc1637 | 72 |
gap | MSMEG0393 | Integral membrane protein. Required for GPL export, + | ma4097c | 58 | mc1638 | 55 |
sap | MSMEG0394 | Sigma-associated protein | ma4454c | 30 | mc1299 | 30 |
ecf | MSMEG0395 | Sigma factor of the ECF family. Required for regulation | ma4459c | 46 | mc1294 | 47 |
fadE5 | MSMEG0396 | Fatty acid desaturase, ° | ma4437 | 78 | mc1318c | 78 |
Rv0926 | MSMEG0397 | None | ma4633 | 36 | mc1136c | 36 |
pks | MSMEG0398 | Fatty acid synthesis and activation, +° | ma0939 | 79 | mc0819 | 79 |
papA3 | MSMEG0399 | Transfer of the Pks-bound fatty acid to the pseudotetrapeptide, ° | ma0938c | 77 | mc0818c | 77 |
mmpL10 | MSMEG0400 | Membrane associated. Interaction with Pks, ° | ma0937c | 75 | mc0817c | 74 |
fadD23 | MSMEG0401 | Long chain fatty acyl-AMP ligase, ° | ma0935c | 73 | mc0815c | 74 |
pe | MSMEG0402 | None | ma0936c | 64 | mc0816c | 66 |
gap-like | MSMEG0403 | Integral membrane protein. Role in the transport of GPLs, ° | ma0934 | 55 | mc0814 | 55 |