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Figure 6 | BMC Genomics

Figure 6

From: Quantitative gene expression assessment identifies appropriate cell line models for individual cervical cancer pathways

Figure 6

Simple media changes to culture conditions increase the HeLa cell line's correlation to cervical cancer. Three pathways provided examples of how the correlation to normal cervix increased when HeLa cells were cultured in rich DMEM media versus ATCC recommended MEM media as monolayers. DMEM media contained glucose, and the expression of PDK4 indicated HeLa cells cultured in DMEM experience a nutrient-rich environment, similar to in vivo conditions.

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