Figure 3

Tamoxifen-induced temporal gene expression patterns. Five k-means clusters best represent the general temporal patterns for the 2941 features differentially expressed following TAM treatment. Note the 8 hr delay in gene expression response especially in comparison to EE elicited gene expression [16] is speculated to be due to the delayed absorption of TAM. Inset numbers indicate the number of features represented by each cluster. Black pseudolines indicate the general profile represented within each cluster.